Under certain conditions, L-Glutamic acid is an essential amino acid. Glutamic acid along with Glutamine, are the dominant amino acids of the cerebrospinal fluid and serum. Known as one of the notorious three musketeers in brain neurochemistry, Glutamic acid is a uniquely powerful brain food, an excitatory neurotransmitter which paradoxically can give rise to GABA, an inhibitory and balancing neurotransmitter within the brain. Glutamic acid is found in concentration within the hippocampus (the memory centers of the brain), in cranial nerves as well as other areas of information transfer to effect motor response. This amino acid is essential for the production of other nonessential amino acids, a process called "transamination."
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